Tobacco contains alkaloids one of them is known as Nicotine. Nicotine has many worst side effect on human body.
It acts on brain and causes depression , in long term use .
Many drugs degradation occur through one or the other degradation path way as that of nicotine.
Thus intake of tobacco , is responsible for elevated enzyme levels which are responsible for degradation of these drugs .
One example of enzyme which is elevated is cytochrome p450.
This is because of metabolic load on liver .
Many anti AIDS drugs are antimetabloites , or enzyme inhibitors , like , Protease inhibitors and Reverse transcriptase inhibitors .
There is a common site on Anit AIDS drugs and Nicotine for all enzyme actions like ,Blocking certain Enzymatic activity, Enzyme oxidation , or transamination , acetylation , or DNA polymerisation.
Thus nicotine may render anti AIDS drug less effective in patients who are smokers or use tobacco , in one or the other form.
i will add more information in coming days on this topic .
This is true for all drugs , excepts few of them who's actions are agonistic with nicotine , the action is vasodialation .
fainting , and so on , which again are not desired .
I have tried to keep this article as small as possible , but this one is a bigger topic , i will update this topic over the time.
It is also observed that the improvement in health of a HIV positive individual greatly affected by smoking
I have come across a new research and development in treating HIV positive peoples . i will write over this blog in coming time , which is going to be one of the best treatment for AIDS.
Source:
HIV and Smoking
So say no to tobacco and smoking.
------------------------------------------------------------------------------------------------------------
This website provide complete information about HIV virus , HIV infection , early HIV symptoms , HIV treatment,HIV test and HIV testing centers, aids symptoms, symptoms of HIV immediately after infection.
------------------------------------------------------------------------------------------------------------
Last updated : 9-Feb-2010
It acts on brain and causes depression , in long term use .
Many drugs degradation occur through one or the other degradation path way as that of nicotine.
Thus intake of tobacco , is responsible for elevated enzyme levels which are responsible for degradation of these drugs .
One example of enzyme which is elevated is cytochrome p450.
This is because of metabolic load on liver .
Many anti AIDS drugs are antimetabloites , or enzyme inhibitors , like , Protease inhibitors and Reverse transcriptase inhibitors .
There is a common site on Anit AIDS drugs and Nicotine for all enzyme actions like ,Blocking certain Enzymatic activity, Enzyme oxidation , or transamination , acetylation , or DNA polymerisation.
Thus nicotine may render anti AIDS drug less effective in patients who are smokers or use tobacco , in one or the other form.
i will add more information in coming days on this topic .
This is true for all drugs , excepts few of them who's actions are agonistic with nicotine , the action is vasodialation .
fainting , and so on , which again are not desired .
I have tried to keep this article as small as possible , but this one is a bigger topic , i will update this topic over the time.
It is also observed that the improvement in health of a HIV positive individual greatly affected by smoking
I have come across a new research and development in treating HIV positive peoples . i will write over this blog in coming time , which is going to be one of the best treatment for AIDS.
Source:
HIV and Smoking
So say no to tobacco and smoking.
------------------------------------------------------------------------------------------------------------
This website provide complete information about HIV virus , HIV infection , early HIV symptoms , HIV treatment,HIV test and HIV testing centers, aids symptoms, symptoms of HIV immediately after infection.
------------------------------------------------------------------------------------------------------------
Last updated : 9-Feb-2010
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