Authored By: B. V Waghmare

Saturday, December 24, 2022

Which are the currently available medicines for treating HIV infection ? What is HAART ?

  Which are the currently available medicines for treating HIV infection ? What is HAART ?
There are following class of Medicines available so far for treatment of HIV infection.
HAART is made up of different kinds of drugs comprising from following categories:

1. Nucleoside Reverse Transcriptase Inhibitors (NRTIs)
2. Nonnucleoside Reverse Transcriptase Inhibitors (NNRTIs)
3. Protease Inhibitors
4. Fusion Inhibitors
5. Integrase Inhibitors
6. Entry Inhibitors
7. Capsid formation inhibitors.
7. Combination Drugs

Here is the detailed list of drugs which are approved by US FDA.
These drugs are mentioned here just for the sec of education and purely for information purpose only , drugs are referred here for reference purpose only for research institutes ,universities and research scientists.

One should not take any drug without consulting his or her doctor , they (doctors) prescribe drugs keeping in view all the side effects and benefits of a drug if there are more harmful side effects which may prove fatal to a patient than actual benefit then such drugs are avoided , hence one should listen and follow doctors instruction regarding medication.

 First Brand name is given and in the bracket generic name of the drug with its abbrivation is provided)
*Nucleoside Reverse Transcriptase Inhibitors (NRTIs)  ---
Combivir (Lamivudine and Zidovudine)
Emtriva (Emtricitabine FTC)
Epivir (Lamivudine 3TC)
Epzicom (Abacavir and Lamivudine)
Hivid (Zalcitabine Dideoxycytidine ddC )
Retrovir (Zidovudine AZT or Azidothymidine, ZDV)
Trizivir (Abacavir, Zidovudine and Lamivudine)
Truvada (Tenofovir Disoproxil and Emtricitabine )
Videx (Didanosine , ddl, Dideoxyinosine)
Videx EC (Enteric Coated Didanosine)
Viread (Tenofovir Disoproxil Fumarate, TDF )
Zerit (Stavudine d4T)
Ziagen (Abacavir Sulfate, ABC)

*Non-Nucleoside Reverse Transcriptase Inhibitors (NNRTIs)
Intelence (Etravirine)
Rescriptor (Delavirdine DLV)
Sustiva (Efavirenz)
Viramune (Nevirapine)

*Protease Inhibitors
Agenerase (Amprenavir APV)
Aptivus (Tipranavir TPV)
Crixivan (Indinavir IDV, MK-639)
Fortovase (Saquinavir (no longer marketed))
Invirase (Saquinavir Mesylate SQV)
Kaletra (Lopinavir and Ritonavir LPV/RTV)
Lexiva (Fosamprenavir Calcium FOS-APV )
Norvir (Ritonavir RTV)
Prezista (Darunavir)
Reyataz (Atazanavir Sulfate ATV)
Viracept (Nelfinavir Mesylate NFV)

*Fusion Inhibitors
Fuzeon (Enfuvirtide T-20 )This medicine is a shot.

*Multi-Class Combination Drugs
Atripla (Efavirenz, Emtricitabine,and Tenofovir Disoproxil Fumarate)

*Integrase Inhibitors
Isentress (Raltegravir)

*Entry Inhibitors
Selzentry (Maraviroc)

* Viral Capsid formation inhibitor drug Lenacapavir.

It is required to form a combination of drugs from almost all class of drugs listed above so that the virus multiplication and count is brought under control.
This is called Highly Active Antiretroviral Therapy. (HAART)



Last updated: 15-Nov-2010

No comments: