Authored By: B. V Waghmare

Thursday, January 15, 2009

HIV-1 drug resistance assay,HIV Information on AIDS|antiAIDS drugs|Information about AIDS medice precise use of anti AIDS Drugs,doing resistance assay

Dear friends i am regularly writing on this blog about latest treatment for AIDS HIV positive and a latest information on HIV virus and Information on AIDS and going research and development on anti AIDS Drugs and anti AIDS HIV vaccines ,i am going to give you here the best information about AIDS medicines,best to best treatment for AIDS.

Today i am going to give you very valuable information on HIV anti aids drugs about

How we can make effective and precise use of available anti AIDS Drugs chemotherapeutic agents ,by knowing which drug is not effective against the virus present in infected individuals body.

This can be achieved by knowing resistance developed by HIV AIDS virus against a particular anti AIDS drug.
Drug resistance means the drug is not giving desired effect on HIV virus , that is HIV virus has developed protective mechanism against this anti AIDS drug.
we all know as and when we are using one particular drug against particular infection ,due to biochemical factors and continues usage of these drugs the bacteria or a virus develops resistance against the drugs being used , rendering these drugs less effective.
Same thing happens with HIV virus
we keep on administrating anti AIDS drugs but on prolonged time HIV virus develops a drug resistance against particular anti AIDS drug

well but there is a technique to over come this drug resistance
this is a purely scientific technique that is to map the Gene on of HIV virus from infected person to find out the all possibilities and any mutation, as mutations are the main cause for drug resistance.
This technique is called HIV -1 drug resistance assay.

The current genotypic PCR based assay amplify and sequence the protease gene and reverse transcriptase gene they are not always able to detect HIV -1 M subtype

most reliable could be Viroseq (Abbot Diagnostics USA)

Some companies in INDIA has developed their own HIV-1 drug resistance assay ,indigenous methods which are very reliable .
This company uses spin column based kit rather than imported ones available in the market its one step reverse transcription kit is routinely used to transcribe the protease and Reverse Transcriptase gene of the HIV viral genome to DNA to make it amenable to polymerase chain reaction.This reverse transcription and subsequent PCR is done by a single tube reaction using a highly convenient one step RT-PCR process using the in house developed kit.
One of the important feature of this assay is availability of back up RT PCR primers .these primers are used when drop out specimens are encountered that fail to respond to the first pairs , these HIV drug resistance assays are capable of scanning 100 codons of protease gene.
A HIV drug resistance interpretation report provides important information on HIV drugs, anti AIDS drug resistance profile of drugs like Nucleoside Reverse Transcriptase inhibitors ,Non Nucleoside Reverse Transcriptase inhibitors , Protease inhibitors .

The HIV Drug resistant assay developed in INDIA provides A SCORING VALUE INDICATION LEVEL OF RESISTANCE AGAINST EACH ANTI AIDS DRUG by a particular HIV virus isolated from infected individual.
This report is very use full tool to decide which drug regimen should be continued for better results for against HIV virus infection. this will help us to bring down HIV virus load to significant lower level so that HIV virus is not detected in blood and semen .
which will definitely save liefs of HIV positive peoples.
About the author of this blog.
Author of this blog is a Pharmacist and he is associated in developing HIV AIDS vaccines and anti AIDS drugs with institute in USA.
This is a reason that you will find some information on HIV AIDS only on this blog and not elsewhere on Internet. This is one of the best information website for AIDS, HIV positive peoples, to find latest update on AIDS treatment, latest research and development over AIDS medicine, so that we can provide best treatment for AIDS , HIV positive peoples.

You can email this blog to your dear and near ones to whom you love most so as to make them aware of importance of preventive steps for HIV AIDS and information on HIV virus and Information on AIDS , by doing this you are joining me in fight against HIV AIDS.
You will find following information about AIDS ,information about HIV virus on following topics on this blog ,
What you have to do is find that over blog Archive on right hand side of this blog.
Latest treatment for AIDS,
How a anti AIDS Drug ,chemotherapeutic drug for AIDS can be designed
What are the difficulties in developing vaccine for AIDS against HIV virus.
what are the latest anti AIDS drugs, current research on AIDS, current research on HIV virus
why there is no vaccine for HIV AIDS. A Detailed information on HIV virus is there on this blog. A Detailed information on AIDS is given on this blog.
A Detailed information about AIDS About HIV Virus is given on this blog. What are the preventive steps for protection against HIV virus What are the current research and developments on HIV virus, vaccine for HIV virus AIDS, and Latest treatment for AIDS. Making use of genetic engineering for providing life saving treatment for AIDS. Gene therapy for AIDS,information about AIDS medicines
Stem cell therapy for AIDS ,using basal stem cells treatment for HIV positive individual. Research on new drugs for HIV AIDS.Every thing about AIDS HIV virus.

AIDS symptoms
HIV symptoms
latest research on AIDS
latest research on HIV
information about AIDS medicines
what is current research on AIDS
What you have to do is search over this blog you will find detailed information on AIDS,Information on HIV virus.and HIV vaccine research a life saving latest treatments available for AIDS.

Information about HIV Virus AIDS symptoms

HIV-1 Drug resistance assay

Signes and symptoms of AIDS and HIV infection-->

Basic Information about HIV and AIDS ==>

This website provided complete information about HIV virus , hiv infection , early hiv symptoms , HIV treatment, HIV test and hiv testing centers, aids symptoms, symptoms of hiv immideately after infection.


Last updated: 15-Jan-2009

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