Authored By: B. V Waghmare

Monday, March 2, 2020

Prevention and mitigation strategy for novel coronavirus infection

How to prevent corona virus infection spread.
Following techniques will provide significant protection from protecting an individual from getting COV19  infection even while living with person infected with Novel Corona Virus.
These techniques are not adapted in china and other countries hence the spread and lethal impact of the outbreak is very huge and life threatening.
In emergency situations masks and sanitisers will not be available since almost all hand sanitizer are Isopropyl alcohol or ethyl alcohol based hand Sanitisers in critical situations they will not be available to general public . 
Therefore alternative decontaminating agent which are not much discussed and hand made cloth masks too can be prepared which can prevent virus transmission.

1)Prevention: (P)

P1) Use Nose mask that contain activated charcoal bed :

How to make activated charcoal Mask ? 

Take adsorbent cotton, make a thin pad by spreading it in thin layer, air should easily pass through this, place thin layer of activated charcoal, make such two layers of activated charcoal and cotton. Take porous cloth and cut it in mask shape, keep these two pads over it, fix it by stitching or by making a bag like, or pocket in mask, and use these mask.
Before making mask use clean cloth, it should be disinfeceted by dipping inside solution of a disinfectant. 
Activated charcoal pads can be replaced in two days with fresh one.

P2) Sanitation and decontamination:
Bleaching Powder Solution :

Very effective and cheaper and widely available sanitizer is bleaching powder . It contains chlorine and it is very powerful decontaminimaging agent it is active against all sorts of Viruses and bacteria.
Make 3 To 5% solution of bleaching powder in water and use this as decontaminimaging agent or as sanitizer.
Sprinkle this solution over the articles and body part which you feel that might be potentially contaminated.
Make continuous thin film of bleaching powder solution over hand or article allow the chlorine react with contamination. It will take about 5 to 10 minutes.
Avoid contact of bleaching powder solution with eyes. Bleaching powder is widely available and is very reliable as disinfectant for virus contaminants.

Dilute solution of Potassium Permanganate:

Dilute solution of Potassium permanganate or sodium Hypochlorite solution to disinfect the flooring and the tabletops, and hand in event of potential risk of patient of corona virus is around the area.
How to make Chlorine disinfectant.
Dissolve about 200 ppm to bleaching 250 ppm powder in water and use 
Make very dilute solution of Potassium permanganate, and use it freshly to decontaminate hand, use as hand wash, higher concentration may cause skin irritation, avoid contact with eye.
Use goggles or spectacles, to protect eyes, decontaminate spectacles with the dilute solution of potassium permanganate.
To decontaminate surrounding use fogger machines or any suitable equipment that generate fumes of the chemical.
Following chemicals can be used to decontaminate infection in environment and in surrounding
  1. Spread bleaching powder in surrounding, since its widely available its best decontaminating agent.
  2. Use H2O2 (Hydrogen Peroxide) in fogger and fog the area where a potential contamination iso.
  3. Wipe the flooring and wall and handrail table top with chlorin water, prepared out of bleaching powder. Use freshly prepared chlorin water from bleaching powder.
  1. Following antimicrobial preparation can be used to decontaminate. Hands, and infected material.
a) Iodine solution, ( Cipladin, Betadine, Wokadine)
b) Mecetronium ethyl sulphate (SterIllium )
c) Silver nitrate solution freshly prepared, d) Iso propyl alcohol, e) Ethyl Alcohol, f)chlorhexidine gluconate containing solutions.

Which body parts to protect.
Avoid touching your eyes, lips and tongue, nostrils, wear spectacles.
Use nose mask containing activated charcoal as described.
As far as possible keep lips closed, avoid speaking without mask.
Protect Ears, a small cotton plug can be used which should be replaced as and when required.

P3) How to protect viral entry in to body 

 Use occlusive methods.
  1. White soft paraffine (Vassaline) is a good occlusive agent, nostrils should be covered from inside with thin layer of white soft paraffine which will protect from viral entry in to body.
  2. Silver sulfadiazine creams can also be used as occlusive barriers inside the nostrils.
  3. Creams containing chlorhexidine gluconate.
Do gargles frequently with water, if there are patients surrounding, use solution of chlorhexidine gluconate to do gargles.

Treatment and medication:
Currently there is no medicine available which is approved by FDA for treatment of novel coronavirus.
Following drugs are recommended after study of the medicinal chemistry and mode of action of the available drugs.
Following suggested medicines best suit for treating the novel corona virus infection.

1.Urgent ayurvedic remedy:
Drink 50 ml of water in which small pinch of Haldi (curcuma longa) is added do not boil after addition of haldI.
Drink this three times a day, do not exceed this.
Haldi contains potent cytotoxic curcumin, which will help in prevention of virus replication in body.

2. Drug for treatment:  (recommendation for medical professionals only)
Following drugs should be used in treatment in combination

A) Combination therapy. (Tetracycline Or Chloroquine + Proteases inhibitors+ Amantadine)
1)Tetracycline + Amantadine+ Protease inhibitor drugs.
In combination with any one drug in following list of protease inhibitors.
Protease inhibitor drugs
Protease inhibitor drugs.
atazanavir (Reyataz)
darunavir (Prezista)
fosamprenavir (Lexiva)
indinavir (Crixivan)
lopinavir/ritonavir (Kaletra)
nelfinavir (Viracept)
ritonavir (Norvir)
saquinavir (Invirase)
tipranavir (Aptivus)
atazanavir/cobicistat (Evotaz)
darunavir/cobicistat (Prezcobix)

B) Combination therapy with (Tetracycline Or Chloroquine+ 5 Flurouracil +Amantadine)

C) Combination Therapy with (Tetracycline +Amantadine+ Any one drug from Nonnucleoside RT inhibitors)

Nonnucleoside RT inhibitors 
1) Rilpivirine
2) Etravirine
3) Delavirdine, DLV
4) Efavirenz, EFV
5) Nevirapine, NVP

Drugs are cytotoxic hence should be taken only after prescription of a medical practitioner.

2.Serum Therapy:
Serum to be separated from infected and cured person and to be used as antibody treatment to person who has got infection recently.

Survival trick:
One can survive even after getting corona virus infection in event, person has got strong lung capability, and has got good immune power.
Yoga is found to be boosting the interlukin 2 system that improves the immunity, therefore yoga will be very important part for patient for survival.

Following Yoga therapy is very important

1)     Yogic cleansing methods
1.      Nostril wash: Yoga kriya :  Neti kriya to be done In event of exposure threat.
2.      Gastric Cleansing : Yoga kriya, Jal Dhauti. In event or after the suspected infection.

3. Boosting immunity :  

Following Yoga Kriyas are very effective in boosting immunity against viral infections, we had done experimentations on HIV patients which we could observe that the body immunity get improved with yoga kriyas.

Shri Ambika Yoga Kutir Thane can be referred for this.

1.Regularly perform : Kapalbhati.
2.Regularly perform Pranayam Kriya: Ujjayi.
3. Omkar Sadhna: Provides heat energy in body due to its unique sound vibrations, boosts immunity.
Not every patient die due to viral infection, person with lower immune power and week lungs are susceptible hence lungs capability can be improvised with yoga, Kapalbhati, and Pranayam kriyas.
Don’t do pranayama, Kapalbhati, Ujjayi kriyas in open environment, but should be done in closed room with clean environment.
Self quarantine:
In event someone is tested positive doctor should confirm with confirmation test PCR technique for presence of viral RNA.
Ensure that you do not spread contamination to others, stay at home, use nose mask and follow the advise provided above.
Do not panic one can survive and get cured from corona virus infection, your fear will bring down the immunity which might be lethal for you, therefore regular yoga practice must be followed.

How to make activated charcoal: 
Activated charocal is easily available in market in good qty.
If its not available it can be made by incernating coconut shels at temprature 900 Deg Celcius.
While temprature is coming down it is spyed with hot steam.
So one should have a steam generating equpment, after taking out the charcoal from the heater or burner, slight steam is exposed over the charcoal.

For Yoga techniques to perform see:




Following link for Information: How yoga is effective in lowering HIV viral load.

ResearchBlogging.org

B V Waghmare (2020). Prevention and mitigation strategy for novel coronavirus infection https://bvwaghmare.blogspot.com/ : DOI

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