How to deal with Recurrent infection serge of corona virus.
Last years in 2020 and 2021 we have faced lock down to
protect ourselves from corona virus and its life threatening infection. Many of
us went through vaccination and even after vaccination lives were lost due
corona infection.
Corona infection acts on the blood and blood vessels,
triggering interleukin flair that caused damage to lungs tissue and due to
embolism, and subsequent events deaths occurred.
Again it is found that after gap of almost one and half
years after successful defeating omicron variant serge again the corona virus
infection cases are increasing.
In a latest finding in a research conducted by national
institute of health it is found that the person infected with corona virus develop
several defects so that the other disease overweighs on the health conditions.
The vaccines are found to produce lesser protective effect
in person with earlier infection history and has not received any vaccination.
In the study it is found that person who are never infected in them vaccines
produced strong protective effect, compared to the person who was previously
infected with corona virus. (reference 1)
The person affected with diabetes and higher cholesterol are
at high risk from the current serge of corona virus.
Therefore, in order
to survive the newer corona infection Yoga Practices should be adapted and practiced daily basis, yoga has found to strengthen immunity.
Treatment for COVID 19, due to the increased number of Omicron (B.1.1.529) Variants of concern. Reference (2)
In Feb 2023 The National Institute of Health of the United
States has published a guideline for providing Treatment for COVID 19, due
to the increased number of Omicron (B.1.1.529) Variants
of concern.
The guideline is an eye opener, when NIH mentioned in it that
the recently developed monoclonal antibodies treatment for treatment of
SARS-COV-2 may not be effective against the Omicron (B.1.1.529).Therefore
it has advised in its guideline that doctors should also give remdesavir
intravenous dosage to out patients as well, the use of remedisavir
was limited to hospitalized patients, while NIH recommend to make use of the
remedisavir in outpatient as well along with NIH in its guideline has
also recommended use of only one monoclonal antibody Sotrovimab 500 mg
Intravenous as a single infusion (AIIa) immediately within 10 days of
symptoms onset.
1.Sotrovimab 500 mg Intravenous as a single infusion (AIIa)
immediately and within 10 days of symptom onset.
2. Remdesivir 200 mg intravenous on day 1, then 100 mg once
daily on Days 2 and 3 (BIIa) initiated as soon as possible and within 7 days of
symptom onset.
Remedesivir intravenous injection requires for three consecutive days therefore it's one of the concerns for outpatients.
Due to the greater variation in spike protein due to
variation in gene sequence the antibodies which were developed with earlier
sequence viz bamlanivimab plus etesevimab and casirivimab plus imdevimab,
may not be effective against the Omicron (B.1.1.529). Therefore, if at all
someone makes use of them, it should be kept in mind that they may not work.
Reference:
(1) Pharma Times